COVID-19: Why young people should worry more

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The aftermath of youth and people recovered from the new Coronovirus remains to be seen and investigated. The disease affects the lungs in such a way that it transforms them into "a burned rubber". Indicated the head of the department of hospital therapy of the National University of Medical Research of Russia, Alexander Chuchalin.

In the opinion of one of the best pulmonologists in Europe, the Russian health system has done its best to protect the country from the coronavirus. According to his assessment, young people affected and recovered by the new Coronavirus will be subject to high mortality in the future.

Coronaviruses are very common viral infections, and people face it many times in their lives. Within a year, a child becomes ill with acute colds up to ten times, and behind these acute colds are certain viruses. And the second place of duration is occupied by the coronavirus. The problem is that these pathogens seem harmless, and were discarded without understanding the cause-effect relationship between a common cold and a virus.

But in 2002, 2012 and currently in 2020, the situation has changed qualitatively, since the infectious microorganisms that have started to circulate affect the epithelial cells; that is, cells that line the surfaces of the body such as the skin, blood vessels, urinary tract, and organs. Therefore, an infected person has lung and intestinal symptoms. This new strain has properties upon contact with the second type of receptor; angiotensin enzyme, associated with a manifestation as serious as cough. Said enzyme regulates cardiovascular hemodynamics and electrolyte balance in body fluids.

Thus, a patient who presents with a cough has the symptom of damage to the lower respiratory tract. The biological target of the virus is the epithelial cells: the nose, the oropharyngeal region, the trachea and then the small bronchioles, being these especially dangerous for humans. And this means that, having this mechanism, the virus leads to a sudden collapse of the immune system.

Why does the coronavirus cause a sudden collapse of the immune system?

Science explains today that it is a protein that is associated with the regulation of innate immunity and acquired immunity. And how can we see this? As deep damage to lymphocytes. If the patient is tested, the white blood cells and increased platelets will appear. It means that you have stable lymphopenia.

The first stage is a harmless cold for 7 to 8 days. From day 9 to day 14 the situation changes qualitatively, because it is during this period that viral and bacterial pneumonia is formed, due to the colonization of microorganisms, mainly in the oropharyngeal region.

The stage where doctors must act skillfully is in the first stage, when it is a mild cold, a runny nose, and the temperature is slightly high. When it passes to the coughing and shortness of breath stage it is a different disease. If this situation is not controlled, the disease progresses to non-cardiogenic pulmonary edema and can only be treated with mechanical ventilation. At this stage the immunosuppression caused by the defeat of the acquired and innate immunity becomes fatal and the patient is affected by pathogens as aggressive as the pseudomonas aeruginosa fungi. Of the cases of death that occurred, 50% of those who were under artificial ventilation filled with fungi in the alveoli.

What is the fate of the man who endured all this?

The infected people suffered a virus period, suffered from viral bacterial pneumonia, respiratory distress syndrome, non-cardiogenic pulmonary edema and septic pneumonia, will they be healthy or not? What is the fate of people who have suffered a coronavirus infection?

This group of people who have had a coronavirus infection develop pulmonary fibrosis within a year, the lung becomes like burnt gum. So, we understand that the immune system will suffer dramatically. We understand the high vulnerability of person to infection that begins to colonize the respiratory tract.

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