Covid Vaccine: 3 New Study Potential Side Effects Revealed
The National Agency for the Safety of Medicines and Health Products (ANSM) in Europe, lists the side effects of the various anti-Covid-19 vaccines in letters addressed to health professionals. Revealing the side effects of Covid-19 serums, from the most frequent to the most rare.
Health authorities also monitor and refer to potential new side effects reported by patients as they occur.
Pfizer, Moderna: EMA studies 3 new potential side effects
On Wednesday, August 11, the European Medicines Agency (EMA) said it was investigating three new potential side effects reported by a small number of people after the Pfizer and Moderna vaccines. Is about :
erythema multiforme, an inflammatory skin disorder characterized by raised, red patches of skin;
glomerulonephritis, a kidney disease that affects the glomeruli, a collection of blood vessels that help filter the blood;
Nephrotic syndrome, which also affects the kidneys and is characterized by excessive excretion of protein in the urine.
Pfizer and Moderna "did not immediately respond to Reuters requests for comment," the news agency said.
As we know: the AstraZeneca vaccine was briefly discontinued in several European and world countries following reports of thrombosis following the injection of this serum. At the same time, the Janssen vaccine was also marked by a suspension in the United States, after cases of thrombosis since it uses the same technology as the AstraZeneca vaccine: they are viral vector vaccines that use an adenovirus to trigger an immune response. This technology could, according to some studies, explain the cases of thrombosis that occur after the administration of these serums.
What are the side effects of the Moderna vaccine?
Since their integration into the vaccination campaign, a large number of cases refer to late local reactions that are not serious, said the health authority. What are the side effects of this anti-Covid-19 serum?
a reaction at the injection site (pain, swelling)
nausea and vomiting
Rare side effects:
Bell's palsy. "Three cases of acute peripheral facial paralysis (Bell's palsy) were reported in vaccinated people in clinical trials in the days after vaccination," adds the ANSM.
Pfizer vaccine: what are its side effects?
In its July 23 report, the ANSM identified 34,790 adverse effects associated with the Pfizer / BioNTech vaccine since the start of the vaccination campaign. However, most of them are considered expected and not serious.
Very common side effects:
Injection site reaction (pain, swelling at the injection site)
Common side effects:
Injection site reaction (redness)
Uncommon side effects:
Pain in the extremities
itching at the injection site
Rare side effects:
Pfizer vaccine: what do we know about myocarditis, pericarditis and pancreatitis?
Rare cases of myocarditis and pericarditis have also been reported to the health authority after administration of this serum. According to the agency, "they occurred within 14 days after vaccination, mainly after the second dose and in young men."
In a second opinion also published on July 23, the ANSM recommended that health professionals be alert to "signs and symptoms associated with myocarditis and pericarditis" after administration of a messenger RNA vaccine. "Health professionals should advise vaccinated people to immediately consult a doctor in case of chest pain, shortness of breath or palpitations," warned the health authority.
In a report published on May 7, the ANSM revealed that six cases of pancreatitis had been observed after the injection of the Pfizer / BioNTech vaccine. A death had also been recorded. "In a third of the cases, they occur in patients with a history of pancreatic or biliary pathologies. The time of appearance is usually short (a few days). This effect constitutes a potential signal and will be shared at the European level," said ANSM.
What are the side effects of the AstraZeneca vaccine?
The AstraZeneca vaccine is only for people 55 and older. At the moment, the ANSM has registered 22,557 adverse effects related to the injection of the serum. This product has also raised many concerns due to the reported cases of thrombosis in patients who received this anti-Covid vaccine.
Almost 10 cases of myocarditis and 38 cases of pericarditis were also reported to the ANSM after administration of the AstraZeneca vaccine. "These facts will be shared at the European level. They do not put in doubt the benefit / risk ratio of the vaccine. We recall that the myocarditis / pericaditis signal has already been confirmed for messenger RNA vaccines (Comirnaty and Spikevax)", had indicated the organization. The health authority has recommended that a health professional be consulted in case of shortness of breath, chest pain, palpitations or irregular heartbeat after the injection of the serum.
Since the start of follow-up, 30 cases of deafness and hearing loss have been recorded after the injection of the AstraZeneca vaccine. These reports "led the committee to consider that this is also a potential signal for the Vaxzevria vaccine. The evolution known to date has been favorable in half of the cases," according to the ANSM.
Sinovac vaccine side effects
The majority of adverse reactions or side effects occurred within 7 days after the vaccine was applied and the majority recovered within 48 hours of the onset of the reaction. Additionally, most of the side effects were mild and transient. Pain at the injection site was the most reported symptom. In this sense, the person who has just received a dose of the Sinovac vaccine should be under observation for 30 minutes if they have a history of allergic reactions or anaphylaxis, if the person does not have any of these conditions they should be under observation for only 15 minutes.
The manufacturer highlights that there are populations for which there are limited or no data on the safety and efficacy of the application of the vaccine, these populations are:
Adults over 60 years: phase III trial with very limited but encouraging data.
People with comorbidities: Its efficacy was tested in patients with hypertension and obesity, but the number of participants with other comorbidities was too small to draw conclusions.
Children and adolescents: There are no safety and efficacy data in those under 18 years of age, but a phase II pediatric study is underway.
Pregnant women: There is insufficient data and tests have only been carried out in animal models. There is also no evidence of safety in lactating women or breastfed children.
The most common systemic reactions with the Sinovac vaccine were headache, fatigue, myalgia, nausea, diarrhea, arthralgia, cough, chills, decreased appetite, vomiting, rash, and fever.